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ISSN: 1553-619X (Print)
ISSN: 1558-3775 (Online)
Research Article Open Access

Advanced Oxidation Protein Products in Aged with Dementia

Melike Erol Demirbilek1, Nedret Kilic1, H. Ferhan Komurcu1 and K. Okhan Akin1
  • 1 Gazi University, Turkey

Abstract

The role of increased oxidative stress in the development of oxidative protein damage in aging have been reported. There is an important role of oxidative stress on development of dementia. Advanced oxidation protein products (AOPPs) are novel markers of oxidative stress. The aim of this study was to compare AOPP levels in healthy aged person and aged person with dementia. AOPP levels were in the control group 83.36 ± 35.51 μmol/L, and 178.78 ± 110.50 μmol/L in the group with dementia. This elevation in the group with dementia was statistically significant (p<0.05). AOPP might be a useful novel indicator of oxidative stress in dementia.

American Journal of Immunology
Volume 3 No. 2, 2007, 52-55

DOI: https://doi.org/10.3844/ajisp.2007.52.55

Submitted On: 13 December 2007 Published On: 31 December 2007

How to Cite: Demirbilek, M. E., Kilic, N., Komurcu, H. F. & Akin, K. O. (2007). Advanced Oxidation Protein Products in Aged with Dementia. American Journal of Immunology, 3(2), 52-55. https://doi.org/10.3844/ajisp.2007.52.55

Open AccessCopyright: © 2007 Melike Erol Demirbilek, Nedret Kilic, H. Ferhan Komurcu and K. Okhan Akin. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Keywords

  • Advanced glycation end products
  • advanced oxidation protein products
  • alzheimer’s disease
  • aging
  • dementia