A Comparative Study between Norethisterone Progestogens and Dydrogesterone in the Treatment of Dysfunctional Uterine Bleeding

Abstract

Problem statement: To compare the effects of both Norethisterone Progestongens and Dydrogesterone in the treatment of Dysfunctional Uterine bleeding Design: A prospective study. Setting: Tikrit Teaching Hospital, Iraq. Approach: About 200 patients presented with abnormal uterine bleeding and diagnosed as dysfunctional uterine bleeding were included in this study. Group A (study group): Include 100 patients were treated with norethisterone progestogens. Group B (control group): Include 100 patients were treated with dydrogesterone the response of the patients were assessed by regularity of menstrual cycle. Results: About 75 patients had regular cycle while 25 patients still had irregular bleeding regarding first group. 46 patients had regular cycle while25 patients still had irregular bleeding regarding second group, decrease in severity of bleeding and resumption of regular cycle were more apparent with Norethiserone drug. Conclusion/Recommendations: Both norethisterone progestogens and dydrogesterone can be used in the treatment of dysfunctional uterine bleeding. Norethisterone progertogens showed higher rates of regular resumption of menses than Dydrogesterone and I recommended to use Norethisertone in the treatment of other problems like regulate ovulation in infertile woman.